Table 2

Features of acute multifocal motor neuropathy with persistent conduction blocks in the four patients from the literature and the four patients in the present series

Abbruzzese et alWhite et alWohrle et alSugie et alpatient onepatient twopatient threepatient four
n., nerve; Igs, immunoglobulins.
Age (years) 5263832532293860
Sex MaleMaleFemaleMaleFemaleMalemalemale
Preceding events DiarrhoeaDiarrhoeaNot reportedDiarrhoeaNoSore throatcorticosteroidsno
Deficit onset time Two weeksA few daysA few daysA few daysA few daysA few daysA few daysA few days
Motor deficit distribution Distal, asymmetric, in all four limbsDistal, asymmetric, in all four limbsAsymmetric, in all four limbsDistal, asymmetric, in all four limbsDistal, asymmetric, in all four limbsGlobal, symmetric, in all four limbsDistal, asymmetric, in all four limbsAsymmetric, in all four limbs
Sensory signs NoNoNoNoNoNoNoYes
Motor relapses YesNoNoNoYesNoYesYes
Persistent motor conduction blocks Bilateral median n. and left peroneal n.Bilateral ulnar n. and left median n.Bilateral ulnar n.Multifocal and distalBilateral median and ulnar n.; left tibial n.Bilateral median, ulnar, peroneal, and tibial n.Bilateral median and ulnar n.; right tibial and left peroneal n.Bilateral median, ulnar, peroneal, and tibial n.
Other electrophysiological abnormalities Reduced distal motor potential amplitudesNoReduced distal motor potential amplitudesNoNoNoNoReduced distal motor potential amplitudes
CSF protein (mg/l) normalnot done0.420.660.60.540.440.55
Campylobacter jejuni positive (recent)positive in stool culturenot donepositivenegativepositive (not recent)negativenegative
Anti-ganglioside antibody IgM anti-GM1, then IgG anti-GM1IgG anti-GM1Negativeanti-GM1, anti-GalNAc-GD1aIgM anti-GM1IgM anti-GM1, IgG anti-GM2IgM anti-GM1negative
Disease evolution recovery after intravenous Igs but relapsesrecovery within a few weeks after intravenous Igsspontaneous recovery within 3 weeksspontaneous recovery within 7 weeksrecovery after intravenous Igs but relapsesrecovery within a few weeks after intravenous Igsrecovery within a few days after intravenous Igsno improvement after intravenous Igs