PON1 −162, −108, 55, and 192 genotype frequencies in cases and controls
| SNP | Genotype | χ2 Genotype distribution | OR* (95% CI) | OR* (95% CI) | ||
|---|---|---|---|---|---|---|
| *OR, odds ratio, adjusted for age (<60, ⩾60) and sex; CI, confidence intervals. | ||||||
| −162 | GG | GA | AA | GA v GG | AA v GG | |
| Cases (%) | 79 (52.7) | 56 (37.3) | 15 (10) | 2.68 | 1.28 | 1.72 |
| Controls (%) | 145 (60.2) | 80 (33.2) | 16 (6.6) | p=0.26 | (0.82 to 1.98) | (0.80 to 3.68) |
| −108 | CC | CT | TT | CT v CC | TT v CC | |
| Cases (%) | 43 (31.6) | 67 (49.3) | 26 (19.1) | 1.34 | 1.09 | 0.75 |
| Controls (%) | 71 (31.1) | 102 (44.7) | 55 (24.1) | p=0.51 | (0.67 to 1.78) | (0.41 to 1.38) |
| 55 | LL | LM | MM | LM v LL | MM v LL | |
| Cases (%) | 60 (40.0) | 70 (46.7) | 20 (13.3) | 0.57 | 1.19 | 0.99 |
| Controls (%) | 105 (43.2) | 104 (42.8) | 34 (14) | p=0.75 | (0.77 to 1.86) | (0.52 to 1.89) |
| 192 | QR | RR | QR v QQ | RR v QQ | ||
| Cases (%) | 81 (54.0) | 57 (38.0) | 12 (8.0) | 0.76 | 0.89 | 0.71 |
| Controls (%) | 121 (50.0) | 97 (40.1) | 24 (9.9) | p=0.68 | (0.58 to 1.37) | (0.33 to 1.51) |