Summary of the techniques described
| Classical | Modern |
|---|---|
| Tissue culture of the nervous system | Polymerase chain reaction (PCR) |
| Virus isolation | Molecular hybridisation methods including in situ hybridisation |
| Electron microscopy | Gene microarrays |
| Serological studies | Molecular analysis of viral isolates |
| Viral antigen detection | Use of viral and animal mutants in neuropathogenesis studies |