Ordinal logistic regression analyses of the relation between possession of one or more APOE ε4 alleles and detailed neuropsychological assessments at late follow up
| Unadjusted analysis | Adjusted analysis* | |||||
|---|---|---|---|---|---|---|
| Outcome measure | Common odds ratio† | 95% CI | p Value | Common odds ratio† | 95% CI | p Value |
| Statistical analysis of the data presented in table 5 of the detailed neuropsychological assessments of outcome in 396 subjects 15 to 25 years after a head injury for carriers and non-carriers of APOE ε4. | ||||||
| *Adjusted for year of injury, age at injury, Glasgow coma score, and pupil reaction at the accident and emergency department, injury type, Glasgow outcome scale at six months, and national adult reading test score. | ||||||
| †A common odds ratio of greater than 1 would indicate that possession of an APOE ε4 allele is associated with poor function. | ||||||
| CI, confidence interval. | ||||||
| Verbal memory | 0.90 | 0.61 to 1.32 | 0.574 | 0.83 | 0.50 to 1.38 | 0.468 |
| Visual memory | 0.92 | 0.63 to 1.36 | 0.690 | 0.94 | 0.56 to 1.56 | 0.806 |
| Attention | 1.22 | 0.83 to 1.81 | 0.307 | 1.54 | 0.94 to 2.53 | 0.089 |
| Language | 1.18 | 0.80 to 1.74 | 0.396 | 1.34 | 0.80 to 2.24 | 0.265 |
| Executive function | 0.98 | 0.67 to 1.45 | 0.938 | 1.23 | 0.74 to 2.06 | 0.421 |