Clinical details and magnetic resonance imaging (MRI) findings in patients with multiple system atrophy (MSA) and with obstructive sleep apnoea syndrome (OSAS)
| MRI findings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Patient | Age (years) | Sex | Disease type | BMI (kg/m2) | Apnoea index (/h) | Desaturation index (/h) | Lowest O2 saturation (%) | Tongue atrophy | Upper airway obstruction | Vocal cord obstruction |
| OSAS data are mean (SD). BMI, body mass index; C, cerebellar MSA; F, female; M, male; P, parkinsonian MSA. Disease types C and P are based on the diagnostic criteria of Gilman et al.12 | ||||||||||
| MSA | ||||||||||
| 1 | 50 | F | C | 29.7 | 28 | 20 | 73 | Complete | Complete | Absent |
| 2 | 73 | M | C | 17.8 | 17 | 4 | 89 | Complete | Complete | Present |
| 3 | 64 | M | C | 29.4 | 39 | 29 | 65 | Complete | Complete | Absent |
| 4 | 56 | M | C | 25.4 | 25 | 10 | 85 | Complete | Complete | Absent |
| 5 | 54 | F | P | 17.8 | 12 | 1 | 95 | Incomplete | Incomplete | Present |
| 6 | 65 | M | C | 19.6 | 14 | 10 | 75 | Incomplete | Incomplete | Absent |
| OSAS (n=20) | M=16 F=4 | 32 (5.5) | 44 (12) | 28 (15) | 70 (10) | Incomplete to complete | Absent | Absent | ||