Influence of the time point of sampling in the disease course on the level of CSF biomarkers
| CJD group | Control group | |||||||
|---|---|---|---|---|---|---|---|---|
| Time point | n | 14-3-3 (AU) | Tau (pg/ml) | Aβ (pg/ml) | n | 14-3-3 (AU) | Tau (pg/ml) | Aβ (pg/ml) |
| A p value was calculated for all groups using the Mann–Whitney U test (*p < 0.05). | ||||||||
| Aβ, β amyloid; CJD, Creutzfeldt–Jakob disease. | ||||||||
| Early | 6 | 0.80* | 2750* | 230 | 12 | 0.00 | 312 | 298 |
| Middle | 39 | 2.01* | 14850* | 316 | 50 | 0.05 | 928 | 345 |
| Late | 7 | 0.89* | 2200* | 257 | 13 | 0.00 | 352 | 201 |