Correlation of immunohistochemical expression in 27 paired initial tumours and first recurrences
| Protein | Initial tumours | First recurrence | p Value* | |
|---|---|---|---|---|
| *χ2 test. | ||||
| Mean score, mean score of positive specimens; †n = 26. | ||||
| p53 | Positive | 24 | 20 | NS |
| Negative | 3 | 7 | ||
| Mean score | 35% | 22% | ||
| mdm2 | Positive | 23 | 17 | p=0.02 |
| Negative | 4 | 10 | ||
| Mean score | 15% | 20% | ||
| EGFR | Positive | 24 | 11† | p<0.0001 |
| Negative | 3 | 15 | ||
| msh2 | Positive | 17 | 5 | p<0.0001 |
| Negative | 10 | 22 | ||
| Mean score | 71% | 64% | ||