Demographic data
| Characteristics | Healthy controls | BMS | SPMS | PPMS |
|---|---|---|---|---|
| No. of subjects | 32 | 13 | 12 | 17 |
| Age (mean (SD)) | 46.1 (7.5) | 47.7 (8.8) | 48.7 (10.6) | 48.6 (13.8) |
| Sex, F/M | 16/16 | 9/4 | 6/6 | 11/6 |
| Disease duration, y (mean (SD)) | – | 21.9 (9.2) | 17.9 (7.1) | 13.5 (4.9) |
| EDSS median (range) | – | 1.3 (0.0–2.5) | 6.6 (4.0–8.0) | 6.2 (4.0–8.5) |
| Leukocyte MPO activity (U/mg protein) | 0.322 (0.053) | 0.086 (0.029) | 0.038 (0.009) | 0.057 (0.016) |