Double blind assessment of the effect of deep brain stimulation (DBS) of the subthalamic nucleus on the motor Unified Parkinson Disease Rating Scale (UPDRS) and timed tests in 10 patients followed up for 4 years
| Assessment | Off DBS | On DBS | p Value | % change |
|---|---|---|---|---|
| UPDRS III | ||||
| Sequence 1 (n = 6) | 49 (58–66) | 30 (13–52) | 38.7 | |
| Sequence 2 (n = 4) | 31 (27–33) | 18 (16–19) | 41.9 | |
| Mean | 43 (27–66) | 26 (13–52) | 0.04 | 39.5 |
| Walking test | 25 (18–27) | 16 (14–20) | 0.04 | 36 |
| Tapping | 114.2 (23–192) | 152.4 (21–223) | 0.04 | 33.4 |