Table 1

Results of cardiovascular autonomic function tests*

Test resultsControlsPossible MSAProbable MSAp Value
NS, not significant.
*Valsalva values are means (SE).
aPost hoc comparisons (p<0.001): controls v patients with probable MSA.
bPost hoc comparisons (p<0.001): patients with possible MSA v patients with probable MSA.
cPost hoc comparisons (p<0.01): controls v patients with possible MSA.
dPost hoc comparisons (p<0.01): controls v patients with probable MSA.
ePost hoc comparisons (p<0.05): controls v patients with possible MSA.
fPost hoc comparisons (p<0.05): controls v patients with probable MSA.
gPost hoc comparisons (p<0.05): patients with possible MSA v patients with probable MSA.
Head-up tilt
    ΔSystolic (mm Hg)1 (1)a,e−14 (3)b,c−40 (5)a,b<0.001
    ΔDiastolic (mm Hg)4 (1)a,e−2 (2)b,e−20 (3)a,b<0.001
Standing
    ΔSystolic (mm Hg)7 (2)a,c−9 (3)b,c−38 (6)a,b<0.001
    ΔDiastolic (mm Hg)7 (2)a,c−4 (3) b,c−18 (3)a,b<0.001
Isometric hand grip
    ΔSystolic (mm Hg)8 (2)3 (2)3 (2)NS
    ΔDiastolic (mm Hg)4 (1)f1 (1)−1 (1)f<0.05
Mental arithmetic
    ΔSystolic (mm Hg)21 (3)a,e7 (4)e1 (3)a<0.001
    ΔDiastolic (mm Hg)9 (2)a5 (3)g−3 (1)a,g<0.001
Cutaneous cold
    ΔSystolic (mm Hg)18 (2)d13 (4)7 (3) d<0.05
    ΔDiastolic (mm Hg)9 (2)8 (2)7 (3)NS
Deep breathing
    ΔHeart rate11 (1)e,f7 (1)e6(1)f<0.05
*Valsalva
    ratio1.43 (0.04)a1.33 (0.05)g1.18 (0.02)a,g<0.001