PD groups | ||||
---|---|---|---|---|
Normals (n=16) | Levodopa naive (n=16) | Treated (n=12) | p value | |
*Note total possible score on this modified UPDRS is only 32. Data shown as mean (SD). | ||||
Age | 57.9 (13.7) | 60.9 (12.3) | 67.7 (6.4) | 0.10 |
Hamilton Depression Scale | 1.0 (1.5) | 2.4 (2.4) | 1.3 (2.6) | 0.22 |
Mini-Mental Status Score | 29.5 (0.9) | 29.2 (0.7) | 28.8 (1.2) | 0.22 |
Baseline Modified UPDRS* | 4.4 (3.2) | 8.1 (5.4) | 0.03 | |
Symptom duration (y) | 3.0 (2.9) | 7.2 (6.0) | 0.02 | |
Treatment duration (y) | 5.5 (5.4) | |||
Modified UPDRS % change after acute dose of levodopa | −39.9 (64.2) | −28.7 (50.1) | 0.62 |