Table 1

Demographic and clinical variables

PD groups
Normals (n=16)Levodopa naive (n=16)Treated (n=12)p value
*Note total possible score on this modified UPDRS is only 32. Data shown as mean (SD).
Age57.9 (13.7)60.9 (12.3)67.7 (6.4)0.10
Hamilton Depression Scale1.0 (1.5)2.4 (2.4)1.3 (2.6)0.22
Mini-Mental Status Score29.5 (0.9)29.2 (0.7)28.8 (1.2)0.22
Baseline Modified UPDRS*4.4 (3.2)8.1 (5.4)0.03
Symptom duration (y)3.0 (2.9)7.2 (6.0)0.02
Treatment duration (y)5.5 (5.4)
Modified UPDRS % change after acute dose of levodopa−39.9 (64.2)−28.7 (50.1)0.62