Regional effects of levodopa on blood flow; SPM99 cluster analysis results
| Cluster level Peak voxel coordinates | |||||
|---|---|---|---|---|---|
| Location of cluster | p value (corrected) | x | y | z | Direction of effect |
| Differential effects of levodopa; treated PD v controls | |||||
| Left VLPFC | 0.049 | −37 | 35 | 3 | Treated PD—decreased blood flow; |
| Controls—increased blood flow | |||||
| Left SMC | 0.036 | −39 | −23 | 47 | Treated PD—decreased blood flow; |
| Controls—increased blood flow | |||||
| Levodopa v baseline; all subjects | |||||
| Midbrain | <0.001 | −9 | −23 | −25 | Increase in blood flow |
| Anterior cingulate | <0.001 | −13 | 31 | 1 | Increase in blood flow |
| Right inferior parietal | <0.001 | 61 | −39 | 11 | Decrease in blood flow |