Table 1

 Characteristics of the 501 patients, submitted to early CT scan according to protocol, and not considered by NICE recommendations

CT negative (n  = 461)CT positive (n  = 40)Odds ratio (95% CI)p value*
CI, confidence interval; *Mann-Whitney U test or Fisher’s exact test: p<0.05; †international normalised ratio in patients with coagulopathy.
Median (IQR) age, years53 (29 to 77)68 (46 to 78)0.054
Median (IQR) INR†2.3 (2.0 to 2.8)2.2 (2.2 to 2.6)0.464
Cause of injury
    Fall204 (44.3%)19 (47.5%)1.14 (0.59 to 2.18)0.741
    Crash179 (38.8%)15 (37.5%)0.94 (0.48 to 1.84)1.000
    Assault15 (3.3%)2 (5.0%)1.56 (0.34 to 7.10)0.637
    Occupational32 (6.9%)2 (5.0%)0.71 (0.16 to 3.06)1.000
Risk factors
    Coagulopathy50 (10.8%)16 (40.0%)5.48 (2.73 to 11.00)<0.001
    Dangerous mechanism156 (33.8%)16 (40.0%)1.30 (0.67 to 2.53)0.488
    Age ⩾65 years191 (41.4%)22 (55.0%)1.73 (0.90 to 3.31)0.133
    History of epilepsy20 (4.3%)2 (5.0%)1.16 (0.26 to 5.15)0.692
    Previous neurosurgery26 (5.6%)1 (2.5%)0.43 (0.06 to 3.25)0.713
    Alcohol and/or drugs51 (11.1%)7 (17.5%)1.71 (0.72 to 4.05)0.205