Evaluation of the interaction of the rs367398 CC genotype with the ϵ4 allele of the APOE gene
| APOE*Notch (p value) | CC versus CT+TT (OR in ε4−) | CC versus CT+TT (OR in ε4+) | |
|---|---|---|---|
| APOE*Notch indicates the significance level of the interaction term included in the logistic regression model. | |||
| OR, odds ratio. Confidence intervals are in given parentheses. | |||
| Scotland, | 0.06 | 0.98 (0.54 to 1.78) | 2.15 (1.11 to 4.20) |
| UK | p<0.82 | p<0.03 | |
| Manchester, | 0.04 | 0.55 (0.20 to 1.52) | 4.75 (0.96 to 23.60) |
| UK | p<0.25 | p<0.06 | |
| Total | 0.002 | 0.83 (0.53 to 1.30) | 2.65 (1.55 to 4.55) |
| p<0.40 | p<0.0004 | ||