Table 2

Allele and genotype frequencies of polymorphisms

Locus	Allele	Allele frequency		p value for allele*	Genotype	Genotype frequency		p value for genotype†
Locus	Allele	Control (n = 936)	AD (n = 780)	p value for allele*	Genotype	Control (n = 468)	AD (n = 390)	p value for genotype†
*Fisher’s exact test and †unbiased estimate of exact p value. The Bonferroni corrected p values for SNP 1 and SNP 7 are given in parenthesis.
SNP 1	C	0.70	0.64	0.01 (0.14)	CC	0.48	0.41	0.01 (0.14)
	T	0.30	0.36		CT	0.45	0.46
					TT	0.07	0.13
SNP 2	C	0.12	0.14	0.36	CC	0.03	0.03	0.54
	T	0.88	0.86		CT	0.19	0.22
					TT	0.78	0.75
SNP 3	C	0.52	0.53	0.92	CC	0.28	0.28	0.98
	T	0.48	0.47		CT	0.49	0.49
					TT	0.23	0.23
SNP 4	C	0.41	0.39	0.50	CC	0.18	0.17	0.73
	T	0.59	0.61		CT	0.46	0.44
					TT	0.36	0.39
SNP 5	C	0.68	0.68	1.00	CC	0.46	0.47	0.62
	T	0.32	0.32		CT	0.44	0.41
					TT	0.10	0.12
SNP 6	C	0.78	0.78	1.00	CC	0.59	0.61	0.62
	T	0.22	0.22		CT	0.37	0.34
					TT	0.04	0.05
SNP 7	G	0.19	0.14	0.01 (0.14)	GG	0.03	0.01	0.01 (0.14)
	A	0.81	0.86		GA	0.31	0.25
					AA	0.66	0.74