Groups | CSF white blood cell count cells/μl | CSF total protein content g/l | CSF to serum albumin ratio ×1000 | blood CD4 cell count CD4/μl | CSF HI-viral load c/ml | Plasma HI-viral load c/ml |
---|---|---|---|---|---|---|
Data are presented as mean (standard error); nd, not done | ||||||
*The CSF WBC count, the total protein levels and the CSF to serum albumin ratio were significantly increased in patients with HIV induced CNS complications compared with HIV negative controls, but not compared with HIV infected patients without CNS complications (p<0.05; Mann Whitney U test). | ||||||
HIV group 1 (n = 19) (no CNS disease) | 3.6 (1.2) | 0.41 (0.02) | 5.3 (0.3) | 248.5 (40.9) | 4830 (2396) | 44834 (13102) |
HIV group 2 (n = 8) (HIV induced CNS disease) | 26.6 (4.3)* | 0.54 (0.10)* | 7.9 (1.1)* | 228.6 (65.8) | 22440 (12716) | 75128 (60506) |
Control patients (n = 18) | 1.7 (0.3) | 0.28 (0.02) | 3.7 (0.3) | nd | nd | nd |