Table 1

 Clinical data and antiganglioside antibody detection in the 29 patients with peripheral neuropathy and cancer

PatientSexAge (years)Delay (months)*EvolutionTypeTumourAnti-GM1 reactivityImmunodot-blot titreELISA titreOther reactivity (immunodot-blot)
*Positive number indicates that the neuropathy preceded the cancer diagnosis and negative number that the neuropathy followed the diagnosis of cancer. In all the cases the neuropathy and the cancer were simultaneously present at least at one time.
†Perivascular inflammatory infiltrates on nerve biopsy.
A, acute; C, chronic; CIDP, chronic inflammatory demyelinating polyneuropathy; DASMN, distal axonal sensory/sensorimotor neuropathy; F, female; GBS, Guillain–Barré syndrome; M, male; SA, subacute; SSN, subacute sensory neuropathy; SCLC, small cell lung cancer.
1M72−36CDASMNUrinary0
2M85−9CDASMNLung (non-SCLC)0
3M63−24CDASMNLung (SCLC)0
4M39+0.5ADASMNThyroid0
5M77−1APlexopathyThymus0
6M73−26CSSNLung (SCLC)0
7M78−2SAAxonal and demyelinatingProstate0
8M65+0.5SAAsymmetrical axonal neuropathy†Tongue+1/1002
9M51−2SADASMNMetastatic adenocarcinoma+1/1002
10F59−7ASSNPET mediastinal fixation0
11M61−6CCIDPLiver+1/5007.1GM2 (1/100)
12M84−7SAAsymmetrical axonal neuropathyLung+1/2003.9
13M74−4CAsymmetrical axonal neuropathy†Urinary+1/2003.3GM3 (1/200)
14M61−1ADASMNStomach0
15F66−36SACIDPMalignant lymphoma0
16F73−26CDASMNPancreas+1/2002.2
17M75−24CDASMNKidney+1/50010GD1b (1/100)
18M73−3SACIDPPancreas0
19M75+2SADASMNTonsil0
20M57−12SASSNLung0
21M48−3SADemyelinating neuropathyMelanoma0
22M73−4CCIDPColon+1/2006
23M65−3SASSNLung0
24M70+3CDASMNMalignant lymphoma0
25M72+22CDASMNMalignant lymphoma+1/5005.9
26M73+0.5SAAxonal and demyelinatingColon0
27M66−1AGBSColon0
28M65−18CAsymmetrical neuropathy†Malignant lymphoma0
29M54−0.5AGBSTongue0