Published recommendations
| Although recommendations for slow correction have been standard for years, what is regarded as “slow” has changed. |
| • Too rapid is >20 mmol/l over 3 days (Norenberg) |
| • If Na+ <105 mmol/l correct at 2 mmol/l/hour for first 20 mmol/l, then allow to drift to normal. If Na+ ⩾105 mmol/l correct at 2 mmol/l/hour to 125–130 mmol/l (Ayus 1985) |
| • Not >12 mmol/l/day for first day, and subsequent days slower (Sterns 1987–1992) |
| • 2.5 mmol/l/hour and no more than 20 mmol/day (Berl 1990) |
| • Not >8 mmol/l/day (Oh 1995) |
| • 15 mmol/l in 24 hours (Kumar and Berl 1998) |
| • <10 mmol/l/day (Laureno and Karp 1997), <10 mmol/l/day in first 24 hours and less on subsequent days (Karp and Laureno 2000) |
| • Should not exceed 1–2 mmol/l/hour and never more than 8 mmol/l/day (Brown 2000) |
| • Should not exceed 8 mmol/l on any day of correction (Adrogue, 2000) |