Table 3

Frequent differences between encephalopathy and encephalitis

EncephalopathyEncephalitis
Reproduced from Davis,7 with permission.
These features are only guidelines for the clinician to help in the distinction between the two conditions. An individual patient is likely to show various combinations of these features.
CSF, cerebrospinal fluid; EEG, electroencephalogram; MRI, magnetic resonance imaging.
Clinical features
FeverUncommonCommon
HeadacheUncommonCommon
Depressed mental statusSteady deteriorationMay fluctuate
Focal neurologic signsUncommonCommon
Types of seizuresGeneralisedGeneralised or focal
Laboratory findings
BloodLeucocytosis uncommonLeucocytosis common
CSFPleocytosis uncommonPleocytosis common
EEGDiffuse slowingDiffuse slowing and focal abnormalities
MRIOften normalFocal abnormalities