Genotype polymorphism, codon 129 | Number of patients | Phenotype | Number of patients | Mean age at onset,years (range) | Mean duration of illness,months (range) |
---|---|---|---|---|---|
Seven of the homozygous 129MM patients had a CJD phenotype instead of a FFI phenotype. The differences in age at onset or duration of illness did not reach statistical significance. | |||||
VV | 0 | – | – | – | – |
MV | 6 | CJD | 4 | 52.5 (38–71) | 19 (2–40) |
FFI | 2 | 52 (50–54) | 17 (15–19) | ||
MM | 17 | CJD | 7 | 56.5 (38–69) | 14.8 (10–20) |
FFI | 10 | 63.2 (37–76) | 10.8 (6–18) |