Hoehn and Yahr score: off | 3.73 | 3.75 | +0.5% | 0.98 |
Hoehn and Yahr score: on | 2.65 | 2.52 | −4.9% | 0.15 |
Schwab and England ADL capacity: off | 37.0% | 41.8% | +13.0% | 0.41 |
Schwab and England ADL capacity: on | 76.4% | 75.2% | −1.6% | 0.70 |
UPDRS ADL (part 2): off | 26.4 | 24.6 | −6.8% | 0.27 |
UPDRS ADL (part 2): on* | 10.5 | 14.1 | +34.3% | 0.031 |
UPDRS motor (part 3): off med–off stim | 43.8 | 46.3 | +5.7% | 0.26 |
UPDRS motor (part 3): on med–on stim | 21.9 | 20.5 | −6.4% | 0.39 |
UPDRS motor (part 3): off med–on stim | − | 32.3 | − | − |
UPDRS (total): off | 70.7 | 70.9 | +0.3% | 0.94 |
UPDRS (total): on* | 32.0 | 34.0 | +6.1% | 0.44 |
MMSE score (out of 30) | 28.1 | 26.6 | −1.5 | 0.052 |
Drug intake (l-dopa equivalents) | 1665 | 1160 | −505 | <0.001 |
Duration of daily off time (hours) | 7.25 | 2.25 | −69% | <0.001 |
Dyskinesia severity‡ | 1.92 | 0.76 | −60.4 | <0.001 |
Weight (kg) | 75.8 | 78.5 | +2.8 | 0.028 |