Results for the three groups
| Hereditary ataxia(group 1) | Idiopathic ataxia(group 2) | Peripheral neuropathy(group 3) | |
|---|---|---|---|
| p Values (in square brackets) calculated by comparison with peripheral neuropathy control population (group 3) except (*) and (**) where p values calculated against English population means of 48.5 and 18.3, respectively.15 | |||
| †DNA samples were not available for all cases. | |||
| Number | 7 | 20 | 32 |
| Male:female | 4:3 | 16:4 | 20:12 |
| Mean age (range), | 51 (36–70) | 60 (34–80) | 66 (32–86) |
| years | |||
| Any AGA (IgG | 3 (43%) | 8 (40%) | 11 (34%) |
| and/or IgA) | [0.132] | ||
| Any AGA and HLA | 2/4 (50%) | 4/8 (50%) | 5/11 (45%) |
| DQ2 positive† | |||
| Any anti-lactoglobulin | 2 (29%) | 6 (30%) | 8 (25%) |
| (IgG and/or IgA) | [0.156] | ||
| Any anti-lactoglobulin | 1/1 | 2/6 (33%) | 2/6 (33%) |
| and HLA DQ2 | |||
| positive† | |||
| Any anti-ovalbumin | 3 (43%) | 5 (25%) | 10 (31%) |
| (IgG and/or IgA) | [1.000] | ||
| Any anti-ovalbumin | 2/3 | 2/5 (40%) | 3/9 (33%) |
| and HLA DQ2 | |||
| positive† | |||
| IgA anti-TTG | 0 | 0 [1.000] | 0 |
| HLA DQ2*† | 4/6 (67%) | 9/19 (47%) | 11/28 (39%) |
| [0.632] | [0.894] | [0.432] | |
| HLA DQ8**† | 2/6 (33%) | 4/19 (21%) | 5/28 (18%) |
| [0.606] | [0.937] | [0.815] | |