Table 1

Specific striatal ¹²³I-FP-CIT binding: clinical data and biochemical data in skeletal muscle

Patient	Age (years)	Clinical diagnosis	Heteroplasmy of mtDNA mutation	CI/CS	COX/CS	NPD	Specific striatal ¹²³I-FP-CIT binding
Control values (n = 21; mean (SD)): CI/CS = 0.11 (0.03); COX/CS = 0.64 (0.18).
CI, complex I; COX, cytochrome c oxidase; CPEO, chronic progressive external ophthalmoplegia; CS, citrate synthase; KSS, Kearns-Sayre syndrome; MELAS, mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes; mtDNA, mitochondrial DNA; NPD, neuropsychological deficit.
1	35	CPEO plus	16% deletion	0.088	0.26	No	3.59
2	40	KSS	78% deletion	0.004	0.05	Yes	3.57
3	40	KSS	62% deletion	0.017	0.08	Yes	2.87
4	43	CPEO plus	26% deletion	0.024	0.12	Yes	3.22
5	46	MELAS	75% A3243G point mutation	0.068	0.43	Yes	3.52
6	51	CPEO plus	53% deletion	0.005	0.10	Yes	3.09
7	53	CPEO plus	58% deletion	0.021	0.10	No	2.90
8	61	CPEO plus	23% deletion	0.071	0.33	Yes	3.09
9	62	CPEO plus	52% A3243G point mutation	0.042	0.17	Yes	2.83
10	69	CPEOplus	<20%, multiple deletions	0.044	0.22	Yes	2.50