Demographic variables of the two study groups
| MC group (n = 170) | KI group (n = 133) | p value | |
|---|---|---|---|
| *Mean (SD); range. | |||
| KI, Karolinska Institutet; MC, Mayo Clinic; MMSE, Mini Mental State Examination; NS, not significant. | |||
| Age (years)* | 78.5 (8.4); | 69.5 (5.8); | <0.0001 |
| 50–98 | 59–81 | ||
| Education (years)* | 13.2 (3.1); | 9.3 (3.0); | <0.0001 |
| 4–20 | 5–18 | ||
| Sex (M/F) | 70/100 | 74/59 | <0.06 |
| MMSE* | 26.0 (2.4); | 25.2 (2.7); | <0.05 |
| 18–30 | 17–30 | ||
| Follow up (months)* | 37.50 (17.72); | 27.55 (17.72); | <0.005 |
| 9–128 | 8–84 | ||
| APOE ε4 genotype | |||
| ε4/4 | 12 (7.1%) | 9 (6.8%) | |
| ε4/3 | 50 (29.4%) | 35 (26.3%) | |
| ε2/4 | 7 (4.1%) | 4 (3%) | NS |
| ε3/3 | 60 (35.4%) | 41 (30.8%) | |
| ε2/3 | 11 (6.5%) | 11 (8.3%) | |
| Missing | 30 (17.5%) | 33 (24.8%) | |