White matter perfusion results (ml/min/100 ml) based on T1 segmentation in all subjects
| Subject | n | WM perfusion ml/min/100 ml (SD) | MS−control difference* | p* | Median T1 lesion volume (range), ml | Median PD lesion volume (range), ml |
|---|---|---|---|---|---|---|
| *Difference adjusted for gender; p value is for this difference compared with controls. | ||||||
| Controls | 34 | 24.2 (4.2) | − | − | 0 | 0 |
| All MS groups | 60 | 27.2 (5.3) | 2.89 | 0.007 | 1.2 (0–15.3) | 5.7 (0.1–52.6) |
| Relapsing remitting | 21 | 27.4 (4.7) | 3.12 | 0.03 | 0.7 (0–8.3) | 4.6 (0.1–52.6) |
| No treatment | 10 | 28.1 (5.3) | 3.72 | 0.04 | 0.6 (0–7.9) | 5.5 (0.3–52.6) |
| On β-interferon | 11 | 26.7 (4.1) | 2.56 | 0.14 | 0.7 (0–8.3) | 3.0 (0.1–22.4) |
| Secondary progressive | 14 | 28.3 (5.7) | 3.72 | 0.02 | 2.8 (0.2–15.3) | 10.3 (1.3–36.8) |
| Primary progressive | 12 | 25.8 (5.0) | 1.62 | 0.33 | 1.7 (0–10.4) | 10.1 (1.3–44.9) |
| Benign | 13 | 27.1 (6.2) | 2.83 | 0.08 | 2.0 (0.3–9.8) | 5.4 (0.9–19.4) |