Baseline demographic data of 71 patients with cryoglobulinaemic neuropathy (CN)
| Variable | “Pure” CN(group 1) | “Comorbid” neuropathy(group 2) | Total | p (1 v 2) |
|---|---|---|---|---|
| *Fisher’s exact test; †t test; ‡Mann–Whitney U test. | ||||
| HCV, hepatitis C virus; NS, not significant. | ||||
| Number | 54 | 17 | 71 | |
| Men/women | 9/45 | 3/14 | 12/59 | NS* |
| Age (in years) at observation (mean (SD)) | 63.6 (9.3) | 67.3 (11.3) | 64.5 (9.8) | NS† |
| Age (in years) at onset (mean (SD)) | 57.7 (9.6) | 63.4 (11.6) | 59.0 (10.3) | NS† |
| Disease duration in years (mean (SD)) | 5.9 (5.8) | 4.1 (5.3) | 5.4 (5.7) | NS† |
| HCV antibodies + (n (%)) | 49 (91) | 15 (88) | 64 (90) | NS* |
| Onset with polyneuropathy (n (%)) | 30 (56) | 3 (18) | 33 (46) | 0.011* |
| Onset with purpura (n (%)) | 42 (78) | 9 (22) | 51 (72) | NS* |
| Rankin score (1/2/3/4) | 16/29/8/1 | 3/10/4/0 | 19/39/12/1 | NS‡ |
| Purpura grading (0/1/2/3/4/5) | 6/9/11/16/10/2 | 2/3/6/4/2/0 | 8/12/17/20/12/2 | NS‡ |
| Hepatopathy staging (0/1/2/3) | 17/29/5/3 | 2/8/6/1 | 19/37/11/4 | NS‡ |