Group 1 (n = 21) | Group 2 (n = 21) | p Value | |
---|---|---|---|
Values are mean (SD) or n where specified. | |||
*Student’s t test for independent samples. | |||
†χ2 test. | |||
‡Fisher’s exact test. | |||
ADL, activities of daily living; BDI, Beck depression inventory; HDRS, Hamilton rating scale for depression; MMSE, mini-mental state examination; UPDRS, unified Parkinson disease rating scale. | |||
Age (years) | 65.3 (7.8) | 66.0 (8.5) | 0.779* |
Male (n) | 11 | 15 | 0.204† |
Female (n) | 10 | 6 | |
MMSE | 24.8 (4.5) | 24.1 (3.6) | 0.597* |
Depression features | |||
HDRS | 25.6 (6.5) | 25.6 (7.5) | 0.775* |
BDI | 25.1 (9.7) | 24.5 (8.8) | 0.843* |
Major depression (n) | 17 | 16 | 1.000‡ |
Minor depression (n) | 4 | 5 | |
Motor threshold, mean | |||
Initial (% output TMS) | 57.0 (11.1) | 54.4 (8.5) | 0.774* |
Parkinsonian features | |||
Age at onset (years) | 58.8 (8.5) | 57.5 (8.9) | 0.621* |
Onset side | |||
Right (n) | 10 | 7 | 0.345† |
Left (n) | 11 | 14 | |
UPDRS | 34.6 (15.3) | 38.1 (17.8) | 0.505* |
ADL | 74.3 (18.3) | 70.9 (21.4) | 0.591* |
Hoehn and Yahr score | 2.1 (1.2) | 2.1 (1.2) | 1.000* |
1 (n) | 8 | 9 | 0.927† |
2 (n) | 6 | 5 | |
3 (n) | 3 | 2 | |
4 (n) | 4 | 5 | |
Drugs | |||
Levodopa (n) | 18/21 | 16/21 | 0.697‡ |
Daily dose (mg) | 472.2 (145.8) | 546.9 (198.3) | 0.217* |