Table 1

 Clinical and demographic characteristic of the EOAD and LOAD patients under study, divided between ApoE E4 carriers (E4+) and non-carriers (E4−)

EOADLOAD
E4−E4+E4−E4+
Values are expressed as mean (SD). FAD, familial AD; SAD, sporadic AD.
n15123431
Age (years)60 (8)65 (5)77 (4)77 (4)
Age at onset(years)54 (6)58 (4)72 (4)73 (4)
Length of illness (months)49 (26)49 (20)46 (18)43 (24)
MMSE22 (5)24 (5)22 (3)23 (4)
Education (years)9 (5)7 (3)9 (4)8 (5)
Gender (men; 
 >women)3 M; 
 >12 W2 M; 
 >10 W13 M; 
 >21 W9 M; 
 >22 W
Familiarity (SAD; FAD)10 SAD; 
 >5 FAD8 SAD; 
 >4 FAD25 SAD; 
 >12 FAD15 SAD; 
 >13 FAD