The ApoE genotype and allele frequencies for 400 AD patients with and without aggression/agitation
| Genotype/allele | Aggression/agitation | |||
|---|---|---|---|---|
| Present | Absent | |||
| No. | % | No. | % | |
| e2/e2* | 2 | 1.0 | 3 | 1.6 |
| e2/e3* | 4 | 2.0 | 9 | 4.7 |
| e2/e4* | 8 | 3.8 | 5 | 2.6 |
| e3/e3* | 76 | 36.5 | 86 | 44.7 |
| e3/e4* | 89 | 42.8 | 72 | 37.5 |
| e4/e4* | 29 | 13.9 | 17 | 8.9 |
| *χ2 = 7.73, df = 5, p = 0.17 | ||||
| e2† | 16 | 3.8 | 20 | 5.2 |
| e3† | 245 | 58.9 | 253 | 65.9 |
| e4† | 155 | 37.3 | 111 | 28.9 |
| †χ2 = 6.69, df = 2, p = 0.03 | ||||
| e2/e2+e2/e3+e3/e3‡ | 82 | 39.4 | 98 | 51.0 |
| e2/e4+e3/e4+e4/e4‡ | 126 | 60.6 | 94 | 48.0 |
| ‡χ2 = 5.45, df = 1 p = 0.02, OR = 1.60, CI 1.06 to 2.43 | ||||