Adverse effects associated with bilateral STN stimulation (deceased patients included)
| Type of adverse event | Number of patients | |
|---|---|---|
| Transient | Permanent | |
| Related to neurosurgery and device | ||
| Urinary retention | 2 | 0 |
| Delirium | 6 | 0 |
| Hypomania | 3 | 0 |
| Repositioning of the electrode | 3 | 0 |
| Infection of the stimulator | 1 | 0 |
| Related to STN stimulation | ||
| Eyelid opening apraxia | 0 | 11 |
| Weight gain | 0 | 12 |
| Muscle contractions | 4 | 0 |
| Hypomania | 1 | 2 |
| Related to medical treatment, | ||
| STN stimulation, or | ||
| progression of the disease | ||
| Disinhibition, loss of emotional | 5 | 8 |
| control | ||
| Addiction to levodopa treatment | 0 | 3 |
| Depression | 8 | 8 |
| Suicide attempt | 4 | 0 |
| Worsening of dysarthria | 0 | 13 |
| Disabling dyskinesias | 3 | 8 |
| Hallucinations | 6 | 0 |
| Psychosis | 4 | 0 |
| Cognitive decline | 0 | 8 |
| Apathy | 4 | 4 |
| Aggressive behaviour | 3 | 0 |