Comparison of Alzheimer’s disease and control groups
| Variable | AD (n = 33) | Normal (n = 137) | p Values | |
|---|---|---|---|---|
| Crude | Age adjusted | |||
| Values are mean (SD) or n. | ||||
| AD, Alzheimer’s disease; AVLT-recall, auditory verbal learning test–recall; Blocks, block design subtest; BVRT, Benton visual retention test; CFT-copy, complex figure test–copy; CFT-recall, complex figure test–recall; Cogstat, composite measure of cognitive impairment; COWA, controlled oral word association; CS, contrast sensitivity; F, female; FVA, far visual acuity; JLO, judgment of line orientation; M, male; NVA, near visual acuity; SFM, structure from motion; TMT-B, trail making test subtest B; UFOVTOT, total of subtests of the useful field of view task; y, years. | ||||
| Demographics | ||||
| Sex (M, F) | 28, 5 | 69, 68 | ||
| Age (y) | 76.1 (6.3) | 64.3 (11.4) | <0.0001 | |
| Education (y) | 15.2 (3.2) | 15.6 (2.5) | 0.3545 | |
| Symptom duration (y) | 2.1 (1.5) | |||
| Cognitive tests | ||||
| Cogstat | 298 (47) | 405 (45) | <0.0001 | <0.0001 |
| AVLT-recall | 3.2 (2.5) | 10.5 (3.0) | <0.0001 | <0.0001 |
| BVRT (errors) | 9.2 (3.2) | 4.4 (2.5) | <0.0001 | <0.0001 |
| CFT-recall | 9.1 (4.5) | 15.8 (5.7) | <0.0001 | <0.0001 |
| JLO | 23.5 (4.1) | 26.2 (3.6) | 0.0005 | 0.0156 |
| Blocks | 23.5 (10.0) | 40.4 (10.8) | <0.0001 | <0.0001 |
| CFT-copy | 28.7 (4.3) | 32.0 (3.3) | <0.0001 | 0.0002 |
| TMT-B | 158 (74) | 79 (39) | <0.0001 | <0.0001 |
| COWA | 34.2 (10.8) | 39.3 (10.8) | 0.0160 | 0.1021 |
| Visual tests | ||||
| NVA | 0.057 (0.068) | 0.018 (0.037) | <0.0001 | 0.0011 |
| FVA | 0.030 (0.113) | −0.098 (0.116) | <0.0001 | 0.0013 |
| CS | 1.64 (0.17) | 1.85 (0.14) | <0.0001 | <0.0001 |
| SFM | 12.7 (7.3) | 10.3 (2.8) | 0.1235 | 0.0067 |
| UFOVTOT (ms) | 1520 (1537) | 615 (236) | <0.0001 | <0.0001 |