Demographic and clinical details of the subjects
| Variable | London cohort(n = 151) | Oxford cohort(n = 188) | Combined(n = 339) | Between cohorts statistical tests |
|---|---|---|---|---|
| MMSE, Mini Mental State Examination; MWU, Mann–Whitney U test. | ||||
| No of men (%) | 31 (21) | 96 (51) | 127 (37) | χ2 p<0.0001 |
| Age in years, median (range) | 82 (30) | 75 (38) | 79 (45) | MWU p<0.0001 |
| Age at onset in years, median (range) | 79 (29) | 72 (42) | 76(45) | MWU p<0.0001 |
| Baseline MMSE score, median (range) | 11 (28) | 22 (23) | 18(30) | MWU p<0.0001 |
| Annual MMSE decline, median (range) | −2.0 (22) | −2.3 (21) | −2.3(22) | MWU p = 0.09 |