Clinical characteristics of patients with different severity of white matter lesions
| Variable | Non-WML (n = 31) | Mild WML (n = 69) | Moderate WML (n = 59) | Severe WML (n = 69) | p Value |
|---|---|---|---|---|---|
| Values are mean (SD) or n (%). | |||||
| *χ2 test, p value <0.05. | |||||
| †One way analysis of variance. | |||||
| DBP, diastolic blood pressure; SBP, systolic blood pressure; WML, white matter lesion; y, years. | |||||
| Male (n) | 21 (67.7%) | 38 (55.1%) | 33 (55.9%) | 38 (55.1%) | 0.818 |
| Age (y) | 50.5 (5.2) | 66.3 (6.7) | 71.0 (5.9) | 75.9 (7.1) | 0.0001† |
| Hypertension (n) | 13 (41.9%) | 34 (49.3%) | 41 (69.5%) | 57 (82.6%) | 0.0001* |
| Duration of hypertension (y) | 2.7 (4.8) | 5.4 (8.1) | 10.3 (11.2) | 13.7 (11.2) | 0.0001† |
| SBP (mm Hg) | 136.3 (26.9) | 146.9 (32.3) | 162.9 (33.8) | 175.2 (30.7) | 0.0001† |
| DBP (mm Hg) | 83.1 (13.9) | 87.0 (14.9) | 92.3 (16.2) | 97.3 (15.6) | 0.001† |
| Diabetes mellitus (n) | 3 (9.7%) | 15 (21.7%) | 17 (28.8%) | 15 (21.7%) | 0.226 |
| Ischaemic heart disease (n) | 1 (3.2%) | 5 (7.2%) | 10 (17.2%) | 18 (26.1%) | 0.004* |
| Atrial fibrillation (n) | 3 (9.7%) | 6 (8.7%) | 6 (10.3%) | 6 (8.7%) | 0.987 |
| Smoking (n) | 10 (32.3%) | 18 (26.1%) | 13 (22.0%) | 21 (30.4%) | 0.659 |
| Alcohol consumption (n) | 6 (19.4%) | 13 (18.8%) | 11 (18.6%) | 17 (24.6%) | 0.805 |