Table 1

 Characteristics of the study population at baseline, with or without serial magnetic resonance imaging

CharacteristicWith follow upWithout follow up
Values are age and sex adjusted means (SD) or percentages unless stated otherwise.
*p<0.05 (analysis of covariance).
ARWMC, age related white matter changes rating scale; MMSE, mini-mental state examination; na, not applicable.
Number of subjects38230
Age at baseline (years)65.9 (8.8)72.3 (9.7)*
Women47.4%60.9%
Mean duration of follow up (years; range)2.2 (1.0 to 5.1)na
Mean ARWMC baseline (range)0.8 (0 to 8)1.8 (3.7)
Mean ARWMC follow up1.5 (0 to 17)na
Hypertension78.4%57.2%
Systolic blood pressure (mm Hg)149.5 (25.8)150.5 (21.9)
Diastolic blood pressure (mm Hg)85.3 (12.3)86.0 (10.5)
Diabetes09.4%
Smoking (ever)32.1%37.8%
MMSE21.4 (4.6)19.7 (5.3)