Analysis of subcutaneous microdialysis samples during 60 minutes before CSF hydrodynamic investigation, during intracranial pressure manipulation (infusion), and for the first 60 minutes after completed drain
| Variable | Baseline (μmol/l) | Infusion (μmol/l) | Drain (μmol/l) | Friedman test |
|---|---|---|---|---|
| The significant change in pyruvate is attributable to one single, very low sample in one patient during the infusion phase; this result might therefore be an artefact. | ||||
| Glucose | 4300 | 4100 | 3900 | NS |
| Lactate | 1682 | 1185 | 1403 | NS |
| Pyruvate | 105 | 76 | 89 | p<0.05 |
| Glutamate | 16.4 | 12.9 | 16.6 | NS |
| Lactate/pyruvate ratio | 16.9 | 19.8 | 16.3 | NS |