Dosing requirements for cholinesterase inhibitors
| • Donepezil |
| – start on 5 mg once a day |
| – if tolerated, increase to 10 mg once a day |
| – maximum dose: 10 mg a day |
| • Galantamine |
| – start on 4 mg twice a day and after 4 weeks increase to 8 mg twice a day |
| – according to response and tolerance, increase to 12 mg twice a day |
| – maximum dose: 12 mg twice a day |
| • Rivastigmine |
| – start on 1.5 mg twice a day and after 2 weeks, increase to 3 mg twice a day |
| – after at least another 2 weeks consider increasing dose to 4.5 mg twice a day |
| – according to response and tolerance the dose can be increased to 6 mg twice a day |
| – maximum dose: 6 mg twice a day |