Crude and multivariate adjusted hazard ratios for ischaemic events as predicted by dichotomised concentrations (< or ⩾ median) of endothelial cell activation markers
| Variable | All ischaemic events | Spontaneous DCI | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude HR | Adjusted HR | Crude HR | Adjusted HR | ||||||||||||
| HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | ||||||||
| vWf: adjusted for amount of intracisternal blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture, day of blood sampling. | |||||||||||||||
| VWf propeptide: adjusted for amount of intracisternal blood, amount of intraventricular blood, day of blood sampling. | |||||||||||||||
| ED1fn: adjusted for amount of intracisternal blood, amount of intraventricular blood, day of blood sampling, loss of consciousness a the time of aneurysm rupture. | |||||||||||||||
| ICAM-1: adjusted for amount of intracisternal blood, loss of consciousness a the time of aneurysm rupture, day of blood sampling. | |||||||||||||||
| sP-selectin: adjusted for amount of intracisternal blood, amount of intraventricular blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture, day of blood sampling. | |||||||||||||||
| sE-selectin: adjusted for amount of intracisternal blood, amount of intraventricular blood, signs of acute ischaemia, loss of consciousness at the time of aneurysm rupture, day of blood sampling. | |||||||||||||||
| CI, confidence interval; DCI, delayed cerebral ischaemia; HR, hazard ratio; vWf, von Willebrand factor. | |||||||||||||||
| vWf ⩾93.0 nmol/l | 2.3 | (1.1 to 4.9) | 1.8 | (0.8 to 3.9) | 3.5 | (0.9 to 13.1) | 2.2 | (0.5 to 9.8) | |||||||
| vWf propeptide ⩾7.70 nmol/l | 1.1 | (0.6 to 2.3) | 0.8 | (0.4 to 1.7) | 1.0 | (0.3 to 3.3) | 0.7 | (0.2 to 2.7) | |||||||
| ED1-fibronectin ⩾2.15 μg/l | 1.2 | (0.6 to 2.4) | 0.9 | (0.4 to 2.0) | 1.8 | (0.5 to 6.1) | 1.5 | (0.4 to 5.4) | |||||||
| sICAM-1 ⩾376.5 ng/ml | 1.0 | (0.5 to 2.1) | 0.9 | (0.5 to 1.9) | 0.9 | (0.3 to 2.9) | 1.3 | (0.4 to 5.0) | |||||||
| Sp-selectin ⩾92.5 ng/ml | 1.5 | (0.8 to 3.1) | 1.5 | (0.6 to 3.3) | 1.3 | (0.4 to 4.2) | 0.8 | (0.2 to 3.1) | |||||||
| sE-selectin ⩾41.5 ng/ml | 0.8 | (0.4 to 1.6) | 0.7 | (0.3 to 1.6) | 0.5 | (0.1 to 1.7) | 0.5 | (0.2 to 1.8) | |||||||