Neuropsychological characteristics at baseline, and at 12 and 24 weeks follow-up examination
| Test | Assessment | Experimental group | IPP control group | ChEI control group |
|---|---|---|---|---|
| ADAS-Cog, Alzheimer’s Disease Assessment Scale-Cognitive; BNT, Boston Naming Test; ChEI, cholinesterase inhibitor; IPP, integrated psychostimulation program; MMSE, Mini-Mental State Examination; RBMT, Rivermead Behavioral Memory Test; SKT, Syndrom Kurztest. | ||||
| MMSE | Baseline | 20.60 (2.10) | 22.50 (2.90) | 22.83 (2.37) |
| Week 12 | 22.53 (2.56) | 23.00 (3.41) | 21.75 (2.26) | |
| Week 24 | 22.07 (3.03) | 22.63 (3.79) | 21.33 (2.23) | |
| ADAS-cog | Baseline | 22.40 (5.70) | 21.19 (5.73) | 20.00 (4.35) |
| Week 12 | 19.86 (4.78) | 18.75 (4.40) | 21.08 (4.52) | |
| Week 24 | 21.33 (5.74) | 22.31 (6.81) | 21.83 (4.48) | |
| SKT | Baseline | 11.80 (3.88) | 11.62 (4.91) | 13.83 (5.72) |
| Week 12 | 12.00 (3.78) | 9.88 (4.03) | 14.58 (5.25) | |
| Week 24 | 12.07 (4.65) | 10.81 (5.10) | 15.16 (5.44) | |
| BNT | Baseline | 36.53 (10.64) | 36.31 (7.04) | — |
| Week 12 | 37.07 (10.05) | 38.63 (7.04) | — | |
| Week 24 | 37.20 (10.26) | 37.25 (8.21) | — | |
| Semantic fluency | Baseline | 10.67 (3.64) | 8.31 (3.14) | — |
| Week 12 | 10.93 (3.04) | 9.13 (3.63) | — | |
| Week 24 | 9.60 (4.41) | 8.75 (4.07) | — | |
| Phonetic fluency | Baseline | 9.53 (3.93) | 8.19 (3.54) | — |
| Week 12 | 9.00 (3.98) | 7.94 (3.89) | — | |
| Week 24 | 9.20 (3.53) | 8.19 (4.09) | — | |
| Story recall subtest(RBMT) | Baseline | 1.73 (1.03) | 2.13 (1.46) | — |
| Week 12 | 2.20 (1.37) | 2.25 (1.69) | — | |
| Week 24 | 2.13 (1.55) | 2.25 (1.48) | — | |