Characteristics | Sequence | |||
---|---|---|---|---|
First amantadine, then placebo | First placebo, then amantadine | |||
MRC, Medical Research Counsil; GBS, Guillain-Barré syndrome; FSS, Fatigue Severity Scale. All baseline characteristics were measured at visit 1. Ranges: *0 to 60; †0 to 6; ‡1 to 7. | ||||
Sex, n | ||||
Female | 19 | 21 | ||
Male | 21 | 19 | ||
Median age at start of study, years (range) | 47.5 (19 to 77) | 52 (24 to 82) | ||
Median duration after diagnosis, years (range) | 3.8 (0.5 to 13.1) | 2.6 (0.5 to 15) | ||
MRC sumscore distribution*, n (%) | ||||
48–57 | 4 (5%) | 8 (10%) | ||
58–59 | 12 (15%) | 7 (9%) | ||
60 | 24 (30%) | 25 (31%) | ||
GBS disability score distribution,† n (%) | ||||
1 | 30 (38%) | 26 (33%) | ||
2 | 7 (9%) | 13 (16%) | ||
3 | 3 (4%) | 1 (1%) | ||
FSS score‡, median (range) | 5.9 (5.1 to 7.0) | 6.0 (5.0 to 7.0) |