Antiparkinsonian drugs before and after surgery
| Medication | Before surgery | 12 months after surgery |
|---|---|---|
| **p<0.0001 for the comparison with the preoperative dose. | ||
| Levodopa (n = number of patients) | 6 | 25 |
| Dopamine agonist (n = number of patients) (sc apomorphine) | 2 [1] | 23 [0] |
| Levodopa+dopamine agonist (n = number of patients) (sc apomorphine) | 89 [26] | 41 [0] |
| Apomorphine repeated injections (n = number of patients) | 23 | – |
| Unitary dose (mg) (mean±SD) (number of injections/day) | 11±4 [1–7] | – |
| Apomorphine continuous infusion (n = number of patients) | 3 | – |
| Flow rate/h (mg) (mean±SD) (number of hours/day) | 5±2 [12–24] | – |
| No drug (n = number of patients) | 0 | 6 |
| Total (n = number of patients) | 97 | 95 |
| Levodopa equivalent daily dose (mg) (mean±SD) | 1240±586 | 506±429** |