Medians and interquartile ranges of the outcomes in early and late intervention groups at tests 1–4
| Test 1 median (Q1–Q3) | Test 2 median (Q1–Q3) | Test 3 median (Q1–Q3) | Test 4 median (Q1–Q3) | |
|---|---|---|---|---|
| CSI, Carer Strain Index; FES, Falls Efficacy Scale; FOGQ, Freezing Of Gait Questionnaire; NEADL, Nottingham Extended ADL Index; PDQ-39, Parkinson’s Disease Questionnaire; PG score, posture and gait score; TGUG, Timed Get Up and Go test. | ||||
| *Falling: time periods of falls diary at each test period differ (test 1 = 3 months, test 2 = 3 weeks; test 3 = 3 weeks; test 4 = 6 weeks). Figures represent numbers of patients who fell. One missing value was obtained at test 1 in the early group and at tests 3 and 4 due to drop-out. | ||||
| Primary outcome | ||||
| PG score (0–20) | ||||
| Early | 6.0 (4.0–8.0) | 4.0 (3.0–7.0) | 4.0 (3.0–6.0) | 4.0 (3.0–7.0) |
| Late | 7.0 (5.0–8.5) | 6.0 (4.0–8.0) | 4.0 (3.0–6.0) | 5.0 (3.0–7.0) |
| Secondary outcomes | ||||
| Walking speed (m/s) | ||||
| Early | 0.86 (0.73–0.98) | 0.94 (0.80–1.1) | 0.94 (0.80–1.1) | 0.92 (0.81–1.1) |
| Late | 0.83 (0.68–0.98) | 0.83 (0.72–1) | 0.93 (0.77–1.1) | 0.94 (0.76–1.1) |
| Step length (m) | ||||
| Early | 0.51 (0.44–0.58) | 0.55 (0.48–0.63) | 0.56 (0.47–0.62) | 0.54 (0.46–0.60) |
| Late | 0.50 (0.43–0.56) | 0.51 (0.43–0.58) | 0.55 (0.47–0.62) | 0.55 (0.48–0.60) |
| Step frequency (steps/min) | ||||
| Early | 101.6 (92.5–110) | 102 (89.4–108.1) | 102.2 (92.5–109.2) | 102.2 (95.2–111) |
| Late | 99 (91.6–109.6) | 102.5 (94.3–112.6) | 101 (94–108.6) | 104.2 (97.2–112) |
| Functional reach (cm) | ||||
| Early | 25.9 (20.9–31) | 26.3 (23–30.5) | 27.5 (20.3–33) | 26.9 (23–31.4) |
| Late | 25.2 (20.2–30.5) | 25.5 (19.8–30.7) | 28.6 (21.6–34.3) | 26.5 (19–31) |
| Single stance (s) | ||||
| Early | 9 (3.8–20.9) | 11.2 (5.3–24.4) | 12 (5.5–23.2) | 11 (5.2–22.1) |
| Late | 9.1 (3.9–21) | 9.5 (3.6–19.3) | 14.2 (6.3–24) | 12.6 (4.2–21.8) |
| Tandem stance (s) | ||||
| Early | 22 (9.3–30) | 26.7 (14.3–30) | 22.0 (11.1–30) | 23.1 (10.4–30) |
| Late | 23.1 (8.0–30) | 20.7 (8.6–30) | 24.6 (11.1–30) | 22.1 (10.2–30) |
| TGUG (s) | ||||
| Early | 13.2 (10.9–17.7) | 12.3 (10.8–15) | 11.8 (10.7–15.7) | 12.2 (11.0–15.6) |
| Late | 13.9 (12.0–17.9) | 12.7 (11.1–15.7) | 12.1 (10.6–15.1) | 12.2 (10.7–15.5) |
| FOGQ (0–24) | ||||
| Early | 8 (4–14) | 8 (3–12) | 7 (3–11.5) | 7 (3–12.5) |
| Late | 8 (4.5–12) | 9 (4–12) | 8 (3–11) | 8 (4–12) |
| NEADL (0–66) | ||||
| Early | 41 (32–53.8) | 42 (33–51) | 42.5 (36.3–53.5) | 46 (35.8–53.3) |
| Late | 40 (35–51) | 42.5 (23.3–54) | 46 (34–51) | 43.5 (35–51) |
| FES (0–130) | ||||
| Early | 85 (65.3–107.8) | 91 (71–111) | 94 (66–110) | 90 (65.5–111.5) |
| Late | 78 (57–99.5) | 82 (54–104) | 85 (70–108.3) | 81 (57.5–105.5) |
| PDQ-39 (total%) | ||||
| Early | 35.4 (22.7–42.6) | 31.3 (22.2–40.9) | 30.9 (20–42.3) | 34.2 (21.8–40.8) |
| Late | 37.8 (27.6–45.9) | 37.2 (25.9–42.7) | 32.3 (20.7–41.4) | 35.6 (22.8–43.5) |
| CSI (0–13) | ||||
| Early | 4 (1–5.8) | 3 (1–4) | 3.0 (1–6) | 1 (0–3) |
| Late | 2 (1–5) | 4 (1–5.5) | 3.0 (0–5) | 1.5 (0–3.3) |
| *Falling (yes/no, % yes) | ||||
| Early | 31/44 (41%) | 18/58 (24%) | 8/67 (11%) | 16/59 (21%) |
| Late | 30/47 (39%) | 14/63 (18%) | 10/67 (13%) | 13/64 (17%) |