Differences in rates of cognitive deterioration between those taking and not taking antipsychotic drugs
| Cognitive test | Deterioration | Statistics | 95% CI/IQR | p Value | |
|---|---|---|---|---|---|
| Taking antipsychotics | Not taking antipsychotics | ||||
| ADAS-cog, Alzheimer’s Disease Assessment Scale—Cognitive Subscale; IQR, interquartile range; MMSE, Mini-Mental State Examination; SIB, severe impairment battery; t, T test; U, Mann–Whitney U test. | |||||
| SIB, median (range) | 3.0 (−34 to 32) | 0 (−22 to 87) | U = 1712.0 | IQR−3–4 | 0.247 |
| MMSE, mean (SD) | 1.0 (3.1) | 0.9 (3.6) | t = −0.2 | 95% CI −1.4 to 1.2 | 0.878 |
| ADAS-cog, mean (SD) | 2.8 (8.0) | 1.4 (8.1) | t = −0.8 | 95% CI −5.0 to 2.1 | 0.421 |