Major depression | No depression | |
n | 15 | 19 |
Volumetrics | ||
Hippocampus | ||
Ipsi | 64 (13) | 71 (18) |
Contra | 93 (18) | 97 (17) |
Amygdala | ||
Ipsi | 76 (19) | 76 (19) |
Contra | 71 (21) | 80 (21) |
T2 relaxometry | ||
Hippocampus | ||
Ipsi | 117 (15) | 120 (10) |
Contra | 102 (7) | 102 (6) |
Amygdala | ||
Ipsi | 102 (15) | 105 (9) |
Contra | 97 (10) | 103 (8)* |
Volumes and T2 relaxation times are expressed as a percentage of normal values based on control values obtained in subjects of the same gender. Differences between depressed and non-depressed patients were assessed by ANCOVA, with age and total brain volume included as covariates for the volumetric measurements, and age for the T2 relaxation times.
*Only patients without depression had a contralateral T2 increase in the amygdala.