Methodological details of the six amyotrophic lateral sclerosis registers used to estimate the epidemiology of amyotrophic lateral sclerosis in Europe
| Sources of case information | Population size | Year case ascertainment commenced | Area (km2) | |
| Ireland4 8 | ALS specialist clinics, neurologists, neurophysiologists, neuropathologists, neurosurgeons, primary care physicians and local charitable organisations | 3 917 203 (2002 census) | 1993 | 70273 |
| Lancashire, UK3 | ALS specialist clinics, neurologists, neurophysiologists, hospital discharge databases | 1 623 667 (2001 census) | 1986 | 5706 |
| Lombardy, Italy7 | ALS specialist clinics, neurologists, neurophysiologists, hospital discharge databases and local charitable organisations | 4 947 554 (2001 census) | 1998 | 23851 |
| Piemonte, Italy5 | ALS specialist clinics, neurologists, and hospital discharge databases | 4 341 733 (2006 est.) | 1995 | 28662 |
| Puglia, Italy6 | ALS specialist clinics, neurologists, hospital discharge database and local charitable organisations | 4 086 613 (2001 census) | 1998 | 19357 |
| Scotland1 2 | ALS specialist clinics, neurologists, neurophysiologists, hospital discharge databases, mortality databases and local charitable organisations | 5 062 011 (2001 census) | 1989 | 78772 |
ALS, amyotrophic lateral sclerosis.