Table 5

Complementary analyses by risk level

Putative risk categories after reclassification
Unexposed*High riskLower riskLowest riskNo risk or not reclassified
Time windowSubjectn (%)n (%)OR (95% CI)n (%)OR (95% CI)n (%)OR (95% CI)n (%)OR (95% CI)
Time window 1 (≥15 years)Cases114 (68.3)0 (0.0)47 (28.1)5 (3.0)1 (0.6)
MC642 (76.9)2 (0.2)132 (15.8)2.13 (1.39 to 3.25)52 (6.2)0.59 (0.22 to 1.55)7 (0.8)0.84 (0.10 to 6.72)
UMC1703 (76.6)6 (0.3)378 (17.0)2.05 (1.42 to 2.96)117 (5.3)0.67 (0.26 to 1.72)20 (0.9)0.80 (0.10 to 6.62)
Time window 2 (5–14 years)Cases117 (70.1)3 (1.8)34 (20.4)7 (4.2)6 (3.6)
MC571 (68.4)8 (1.0)1.85 (0.49 to 6.96)188 (22.5)0.88 (0.59 to 1.33)48 (5.7)0.71 (0.31 to 1.61)20 (2.4)1.47 (0.57 to 3.79)
UMC1512 (68.0)11 (0.5)3.43 (1.01 to 11.6)531 (23.9)0.83 (0.56 to 1.24)123 (5.5)0.76 (0.34 to 1.68)47 (2.1)1.57 (0.64 to 3.85)
Time window 3 (1–4 years)Cases136 (81.4)1 (0.6)22 (13.2)7 (4.2)1 (0.6)
MC692 (82.9)3 (0.4)1.68 (0.17 to 16.3)104 (12.5)1.07 (0.66 to 1.76)21 (2.5)1.70 (0.72 to 4.01)15 (1.8)0.32 (0.05 to 1.84)
UMC1831 (82.3)12 (0.5)0.89 (0.12 to 6.67)281 (12.6)0.89 (0.55 to 1.43)59 (2.7)1.46 (0.65 to 3.26)41 (1.8)0.29 (0.04 to 2.07)
  • OR for comparisons with unmatched controls (UMC) was adjusted by age, sex and country.

  • * Reference category. No registered surgery.

  • MC, matched controls.