Clinical profiles of POEMS syndrome and CIDP patients
| POEMS (n=51) | CIDP (n=46) | p Value | |
| Clinical profile | |||
| Age (years) | 53 (11) | 44 (20) | 0.01 |
| M:F | 35:16 | 29:17 | 0.6 |
| Hughes grade | 3 (1–4) | 3 (2–4) | 0.7 |
| Time to Hughes grade 3 (months) | 7 (1–50) | 2 (1–6) | 0.5 |
| Neurological feature | |||
| Cranial nerve palsy | 2% | 18% | 0.009 |
| MRC score | |||
| Deltoid | 5 (3–5) | 4 (1–5) | 0.006 |
| Wrist extensor | 5 (2–5) | 4 (1–5) | 0.003 |
| Iliopsoas | 4 (1–5) | 4 (1–5) | 0.4 |
| Tibialis anterior | 2 (1–5) | 4 (1–5) | 0.03 |
| Muscle atrophy | |||
| Upper extremity | 37% | 22% | 0.1 |
| Lower extremity | 52% | 24% | 0.005 |
| Sensory symptom | |||
| Dysesthesia/paresthesia | 98% | 83% | 0.01 |
| Pain | 76% | 7% | <0.0001 |
| Pain sensory loss | 69% | 83% | 0.09 |
| Vibratory sensory loss | 96% | 92% | 0.8 |
| Areflexia | 98% | 100% | 0.9 |
| CSF protein (mg/dl) | 126 (73) | 154 (163) | 0.4 |
Data are expressed as mean (SD), median (range) or per cent.
CIDP, chronic inflammatory demyelinating polyneuropathy; MRC, Medical Research Council; POEMS syndrome, polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes syndrome.