Author | n | Study design | Measurement instrument OC symptom | OC symptom severity*† ‡ | Measurement instrument OCD diagnosis | OCD diagnosis† ‡ |
Chorea | ||||||
Huntington's disease | ||||||
Anderson et al26 | 27 | Cohort | Y-BOCS | –¶ | – | – |
Anderson et al27 | 1642 | Cohort | UHDRS | –¶ | – | – |
Beglinger et al28 | 3964 | Cohort | UHDRS | –¶ | – | – |
Beglinger et al29 | 300§ | Case control | SCOPI | – | – | |
Craufurd et al20 | 134 | Cohort | PBA-HD | –¶ | – | – |
van Duijn et al30 | 140§ | Case control | – | – | CIDI | ‡ |
Murgod et al31 | 26 | Cohort | UHDRS | –¶ | – | – |
Sydenham's chorea | ||||||
Alvarenga et al32 | 51§ | Case control | Y-BOCS | ‡ | – | † |
Asbahr et al33 | 50 | Case control | LOI (resistance) | K-SADS | † | |
LOI (interference) | Month 5+6† | |||||
Asbahr et al34 | 73 | Cohort | Y-BOCS | –¶ | – | – |
Asbahr et al35 | 38§ | Case control | Y-BOCS | † | – | – |
Hounie et al36 | 59§ | Case control | Y-BOCS | † | SCID | † |
Hounie et al37 | 50§ | Family study** | Y-BOCS | ‡ | SCID, K-SADS | † |
Maia et al38 | 106§ | Case control |
| ‡ | K-SADS | ‡ |
| ‡ | |||||
Mercadante et al39 | 42§ | Case control | Y-BOCS | † | K-SADS | † |
Dystonia | ||||||
Myoclonus dystonia | ||||||
Foncke et al40 | 27§ | Family study** | Y-BOCS | † | SCID | |
Saunders-Pullman et al,41 Hess et al42 | 30§ | Family study** | – | – | CIDI | |
Generalised dystonia | ||||||
Heiman et al43 | 27§ | Case control | MOCI | CIDI | ||
Blepharospasm | ||||||
Bihari et al44 | 21§ | Case control | MOCI | ‡ | – | – |
Broocks et al45 | 13§ | Case control |
| – | – | |
Hall et al46 | 159§ | Case control | HOCI | † | – | – |
Munhoz et al47 | 30§ | Case control | Y-BOCS | † | – | † |
Wenzel et al48 | 31 | Cohort | – | – | SCID | † |
Idiopathic focal dystonia | ||||||
Cavallaro et al49 | 76§ | Family study** | Y-BOCS | –¶ | – | ‡ |
Fabbrini et al50 | 86§ | Case control | Y-BOCS | † | – | – |
Lencer et al51 | 86§ | Case control | – | – | SCID | ‡ |
Idiopathic spasmodic torticollis | ||||||
Bihari et al52 | 22§ | Case control |
| – | – | |
Focal hand dystonia | ||||||
Voon et al53 | 39 | Cohort | – | – | SCID | –¶ |
Characteristics of the 29 included studies regarding patients with movement disorders and comorbidity with OCD.
↵* OC symptom severity in study group compared with control group.
↵† No difference between case and controls.
↵‡ Significant difference between case and controls.
↵§ Only the case group is listed.
↵¶ No information available or study design not suitable for comparison.
↵** Only the probands of the family studies are presented.
CIDI, Composite International Diagnostic Interview; HOCI, Hamburg Obsession/Compulsion Inventory; K-SADS, Schedule for Affective Disorders and Schizophrenia for School Aged Children; LOI, Leyton Obsessional Inventory-child version; MMC, manifest mutation carrier; MOCI, Maudsley Obsessive–Compulsive Inventory; NMC, non-manifest mutation carrier; OCD, obsessive–compulsive disorder; PBA-HD, Problem Behaviours Assessment for Huntington's Disease; PD, Parkinson's disease; SCID, Structured Clinical Interview for DSM-IV Axis I Disorders; SCL-90-R, Symptom Check-List-90-revised; SCOPI, Schedule of Compulsions; UHDRS, Unified Huntington's Disease Rating Scale; Y-BOCS, Yale–Brown Obsessive–Compulsive Scale.