Median changes in individual test scores for each subjective response group
| Follow-up 1 | p Value | Follow-up 2 | p Value | |||||||||
| No improvement (n=22) | <25% improvement (n=27) | 25–49% improvement (n=33) | 50–75% improvement (n=42) | >75% improvement (n=9) | No improvement (n=13) | <25% improvement (n=15) | 25–49% improvement (n=24) | 50–75% improvement (n=45) | >75% improvement (n=9) | |||
| UPDRS (II)* | −3.0 (−10.0 to 1.5) | −1.0 (−1.0 to −1.0) | −2.0 (−4.3 to 2.5) | −1.5 (−8.0 to −0.3) | −6.0 (−6.0 to −6.0) | 0.843 | −2.0 (−5.0 to 0.0) | 0.0 (−2.8 to 0.8) | −3.0 (−7.5 to 0.0) | −3.0 (−5.0 to −0.3) | −6.0 (−7.5 to −1.5) | 0.204 |
| UPDRS (III)* | −3.0 (−10.0 to 3.0) | −6.0 (−10.0 to 1.0) | −5.0 (−10.0 to −2.5) | −10.0 (−15.3 to −4.0) | −14.0 (−19.5 to −8.0) | 0.004 | −4.5 (−11.5 to 0.0) | −8.0 (−13.0 to −2.0) | −7.0 (−14.0 to −2.0) | −7.5 (−12.0 to −3.3) | −14.5 (−19.5 to −1.3) | 0.534 |
| PDQ39* | 3.7 | 8.7 | 3.9 (−17.1 to 11.2) | 1.0 (−6.5 to 9.0) | −0.7 | 0.891 | 4.0 (−0.1 to 5.5) | −0.8 (−7.4 to 7.5) | 0.0 (−5.1 to 2.5) | 1.0 (−4.2 to 4.0) | −7.0 (−23.3 to 8.4) | 0.387 |
| Timed walks* | 2.0 (−5.0 to 2.0) | −1.0 (−4.0 to 1.5) | −0.5 (−3.3 to 1.0) | −2.0 (−6.0 to 1.0) | −7.5 (−12.5 to −0.3) | 0.375 | 1.5 (0.0 to 4.3) | 0.0 (−2.0 to 3.5) | −1.0 (−6.5 to 2.0) | −1.0 (−3.0 to −1.0) | 0.0 (−4.0 to 1.5) | 0.063 |
| Worst taps† | 1.0 (−3.0 to 1.5) | 4.5 (1.3 to 6.8) | 4.0 (−3.0 to 6.5) | 4.0 (0.5 to 7.5) | 6.5 (1.5 to 13.8) | 0.155 | 2.0 (−3.0 to 3.0) | 3.0 (−2.0 to 7.0) | 6.0 (3.3 to 13.5) | 5.0 (2.0 to 9.0) | 5.0 (0.0 to 16.0) | 0.051 |
Data are median (IQR).
↵* Negative value indicates improvement over time.
↵† Positive value indicates improvement over time.
PDQ-39, Parkinson's Disease Questionnaire, full version; UPDRS (II) and (III), Unified Parkinson's Disease Rating Scale, activities of daily living and motor subsections, respectively.