Time (age) to EDSS or DSS end point (years) | ||||||||
---|---|---|---|---|---|---|---|---|
Study | Country | N | Age limit | 3.0 | 4.0 | 6.0 | 7.0 | 8.0 |
Simone et al8 | Italy | 83 | <16 | – | 20.2 (31.6) | – | – | – |
Boiko et al5 | Canada | 116 | <16 | 16.0 (28.5) | – | 19.4 (32.3) | – | – |
Renoux et al6 | France, Belgium | 394 | <16 | – | 20.0 (34.6) | 28.9 (42.2) | 37.0 (50.5) | – |
Present study | UK | 111 | <18 | – | 23.8 (40.1) | 30.8 (45.4) | – | 44.7 (54.8) |
DSS, Disability Status Scale; EDSS, Expanded Disability Status Scale; POMS, paediatric-onset multiple sclerosis.