Distribution of the COMT Val158Met polymorphism in PD and controls
| Total (% (n)) | Control (% (n)) | PD (% (n)) | p Value | |
|---|---|---|---|---|
| Val/Val | 23.7 (3943) | 23.6 (2526) | 24.1 (1417) | 0.22 |
| Val/Met | 49.5 (8214) | 49.5 (5303) | 49.5 (2911) | |
| Met/Met | 26.8 (4452) | 27.0 (2894) | 26.5 (1558) |
Val/Val: homozygous for the Val158 allele; Val/Met: heterozygous; Met/Met: homozygous for the Met158 allele. p Value: multivariate analysis (see material and methods).
COMT, catechol-O-methyltranferase; PD, Parkinson's disease.